Open Access

Potential benefits of garlic and other dietary supplements for the management of hypertension (Review)

  • Authors:
    • Toshiaki Matsutomo
  • View Affiliations

  • Published online on: December 27, 2019     https://doi.org/10.3892/etm.2019.8375
  • Pages: 1479-1484
  • Copyright: © Matsutomo . This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Elevated blood pressure is a major risk factor for cardiovascular diseases. Although some effective drug treatments are available, a relatively large proportion of patients have uncontrolled blood pressure. Dietary supplements are used for the prevention and treatment of hypertension as complementary and alternative medicines. Of the various dietary supplements, antioxidants, fish oil and diverse herbal products are commonly used. Within this context, it is important to determine the actual effectiveness and possible side‑effects of these supplements; however, some of the products have been poorly investigated for their effects and safety. In the current review, we focus on garlic and several other dietary supplements, such as coenzyme Q10, fish oil and probiotics, that have exhibited significant beneficial effects on blood pressure in clinical trials. In addition, we discuss the possible mechanisms of action responsible for their anti‑hypertensive effects, as well as the safety, active ingredients and their potential use as adjunct therapies for uncontrolled hypertension.
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February-2020
Volume 19 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Matsutomo T: Potential benefits of garlic and other dietary supplements for the management of hypertension (Review). Exp Ther Med 19: 1479-1484, 2020.
APA
Matsutomo, T. (2020). Potential benefits of garlic and other dietary supplements for the management of hypertension (Review). Experimental and Therapeutic Medicine, 19, 1479-1484. https://doi.org/10.3892/etm.2019.8375
MLA
Matsutomo, T."Potential benefits of garlic and other dietary supplements for the management of hypertension (Review)". Experimental and Therapeutic Medicine 19.2 (2020): 1479-1484.
Chicago
Matsutomo, T."Potential benefits of garlic and other dietary supplements for the management of hypertension (Review)". Experimental and Therapeutic Medicine 19, no. 2 (2020): 1479-1484. https://doi.org/10.3892/etm.2019.8375