Open Access

COVID‑19‑associated acute appendicitis in adults. A report of five cases and a review of the literature

  • Authors:
    • Vasiliki Epameinondas Georgakopoulou
    • Aikaterini Gkoufa
    • Christos Damaskos
    • Petros Papalexis
    • Aikaterini Pierrakou
    • Sotiria Makrodimitri
    • Georgia Sypsa
    • Apostolos Apostolou
    • Stavroula Asimakopoulou
    • Serafeim Chlapoutakis
    • Pagona Sklapani
    • Nikolaos Trakas
    • Demetrios A. Spandidos
  • View Affiliations

  • Published online on: June 1, 2022     https://doi.org/10.3892/etm.2022.11409
  • Article Number: 482
  • Copyright: © Georgakopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The novel coronavirus has negatively affected patients and healthcare systems globally. Individuals with coronavirus disease 2019 (COVID‑19) experience a wide range of respiratory symptoms, from mild flu‑like symptoms to severe and potentially fatal pneumonia. Some patients report gastrointestinal symptoms, such as nausea, vomiting and abdominal pain in addition to the respiratory symptoms or as a separate presentation. Even though abdominal pain syndrome indicates acute appendicitis, severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection should be considered as a possible diagnosis during this pandemic. However, there have been reports of a few cases of acute abdominal pain revealing acute appendicitis associated with SARS‑CoV‑2 infection. Appendectomy is challenging in COVID‑19‑infected patients with acute appendicitis as it includes high surgical risks for the patients, as well as hazards for healthcare professionals who are exposed to SARS‑CoV‑2. The present study reports five cases of adult patients with COVID‑19 with simultaneous acute appendicitis. In addition, the present study aims to provide the framework for the diagnosis and management of adult patients with COVID‑19 with acute appendicitis.
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July-2022
Volume 24 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Georgakopoulou VE, Gkoufa A, Damaskos C, Papalexis P, Pierrakou A, Makrodimitri S, Sypsa G, Apostolou A, Asimakopoulou S, Chlapoutakis S, Chlapoutakis S, et al: COVID‑19‑associated acute appendicitis in adults. A report of five cases and a review of the literature. Exp Ther Med 24: 482, 2022.
APA
Georgakopoulou, V.E., Gkoufa, A., Damaskos, C., Papalexis, P., Pierrakou, A., Makrodimitri, S. ... Spandidos, D.A. (2022). COVID‑19‑associated acute appendicitis in adults. A report of five cases and a review of the literature. Experimental and Therapeutic Medicine, 24, 482. https://doi.org/10.3892/etm.2022.11409
MLA
Georgakopoulou, V. E., Gkoufa, A., Damaskos, C., Papalexis, P., Pierrakou, A., Makrodimitri, S., Sypsa, G., Apostolou, A., Asimakopoulou, S., Chlapoutakis, S., Sklapani, P., Trakas, N., Spandidos, D. A."COVID‑19‑associated acute appendicitis in adults. A report of five cases and a review of the literature". Experimental and Therapeutic Medicine 24.1 (2022): 482.
Chicago
Georgakopoulou, V. E., Gkoufa, A., Damaskos, C., Papalexis, P., Pierrakou, A., Makrodimitri, S., Sypsa, G., Apostolou, A., Asimakopoulou, S., Chlapoutakis, S., Sklapani, P., Trakas, N., Spandidos, D. A."COVID‑19‑associated acute appendicitis in adults. A report of five cases and a review of the literature". Experimental and Therapeutic Medicine 24, no. 1 (2022): 482. https://doi.org/10.3892/etm.2022.11409